E3 ligases s & epidermal architecture, progenitors, mechanisms of UV-caused SCC

Readings due before class

Required

Dr. Caroline Schild-Poulter’s readings:

• Senft et al. (2017) Ubiquitin ligases in oncogenic transformation and cancer therapy

• Dale et al. (2021) Advancing targeted protein degradation for cancer therapy

Dr. Lina Dagnino’s readings:

• McHugh et al. (2020) The identification of potential therapeutic targets for cutaneous squamous cell carcinoma

• Fania et al. (2021) Cutaneous Squamous Cell Carcinoma: From Pathophysiology to Novel Therapeutic Approaches

• Tang, Kinwah, Chan (2021) Incidence and mortality rates of keratinocyte carcinoma from 1998–2017: a population-based study of sex differences in Ontario, Canada

Complementary reading

Action items

Points of reflection